There’s never a dull moment.
Earlier today, I read a paper from Nature titled “Nascent transcript sequencing visualizes transcription at nucleotide resolution*”. The paper describes a very cool new technique that allows you to see gene transcript sequences as they are being made. The authors demonstrate that this method can be used to sequence unstable, short-lived pre-modification mRNAs; quantify sense and antisense transcript abundance; identify proteins that regulate promoter directionality; and map transcription pause sites.
Cool stuff, right?!
(If you’re not in this field: trust me on this. It’s megasupercool).
So, this article being in the same issue of Nature as a feature on rapid online post-publication review (“Peer review: Trial by Twitter“), I obviously had to tweet about it. And that’s when the fun began:
In no time at all, Bob maded me a LOLcat, and then he eated tweeted it:
Ribosome Polymerase Kitteh iz teh LOLz!
The Nature feature on online peer review says:
“Unstructured, unruly and often anonymous, online commenting can be exasperating for biologists used to more conventional means of discussion”.
I can’t possibly think why.
*Full citation: Churchman LS, Weissman JS. Nascent transcript sequencing visualizes transcription at nucleotide resolution. Nature 2010: 469:368-373.
I’d also just like to say that Stirling Churchman is an awesome name.