In which I preserve

I often think about how ancient survival strategies are probably still encoded somewhere deep in our chromosomes, cryptic and dormant but with the potential to be roused by the faintest of stimuli.

For me, recent unrest in the world has woken up some vestigial feelings. Social and traditional media are full of black times, news feeds spewing out calculated falsehoods, threats, abuse, close-mindedness, propaganda, pessimism – and ever other kind of -ism you’d ever not want to see in one lifetime. I try to walk a fine line between keeping informed and protecting myself from the worst of the onslaught. Otherwise, it’s impossible to stay productive – despite the more relaxed summer academic vibe, I still have a million and one tasks that need doing, and a team of scientists to supervise with a clear head.

Brexit is one of the things in the daily onslaught that worries me the most. I wouldn’t classify myself as either of the two patronizing categories currently in circulation (“remoaner” and “remainiac”), but I did vote for Britain to stay in Europe and I am heartily concerned at how terribly the Government is handling the negotiations. I don’t believe there will be any sort of apocalypse afterwards, but I do think it could take a few decades for the nation to stablize – at which point I’ll be gone, or close to, from this planet. I know that I am far better off than most, but still I am saddened that my chances at a pleasant denouement after a long life of working so hard will likely be materially harmed by a generation of sluggish economic growth.

This is my rational mind talking. But somewhere deep within, my body is preparing for some sort of immediate disaster come March of next year, no doubt fuelled by speculation in the media about supply-chain problems immediately after Brexit. (Actually, I’m not sure it’s even irrational to think there might be a period of food shortages, with trade so finely balanced and with retail supermarkets not being geared up to storing or refrigerating anything extra.)

Seeing as I spend so much of my spare time in a hard-working garden, it’s probably not a surprise that I’ve been thinking more carefully than usual about the bounty of fruits and vegetables currently glutting around me. In fact, I’m almost obsessed – hence my idea that instinct might be kicking in. Richard and I always have done lots of preserving: jams, jellies, pickles, chutney, wines and ciders. But this year it’s felt different to me, more relevant and urgent. I may joke that one day soon we might be trading quince jelly for ammo, but underneath the humor is something imperative that I don’t understand and am loathe to dismiss outright.

So I pick far more fruit than we will ever need, sacrificing precious reading and writing time to labor long after evening has fallen, scratching my hands on brambles and stinging my ankles on nettles. I save sweetcorn cobs desiccated by the draught to grind into meal, even though extracting the kernels is a tedious business. I research the best way to crack open sunflower seeds en masse. I collect coriander seed, linseed and fennel seeds for seasoning or infusions. I get more serious about saving seeds from the heritage vegetables that we currently have, preparing and drying and labelling them carefully in white envelopes for germination next year. Our fruit drier is going 24/7 – plums, figs, apples, chilis, whatever’s going – and Richard has lots of fermentation in progress, gurgling away in the corner of the utility room. We sow winter crops now in beds cleared of summer’s efforts, and think ahead to what will go in come early spring. And above all, we enjoy what we have in real time: fresh pesto from our basil pots; salsa verde from tomatillos, onion and coriander; deep-friend courgette flowers. Joshua wanders around in paradise, picking and eating what he finds, and will grow up thinking this is normal.

Or, I can only trust that it will remain so, even after we leave.

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In which Cat Zero arrives on the scene; plus some other literary shenanigans

It’s nearly showtime: my third lab lit novel Cat Zero is about to be published! After a several-month delay due to issues of US distribution, I am pleased to confirm an official publication date of Tuesday 5 June!

Yes, that’s next Tuesday! Just today, as I was working from home on various academic tasks, the postman rang the doorbell and delivered a few boxes of books hot off the presses:

Cats in a box – no relation to Schrödinger’s

Set in present-day England, Cat Zero relates the tale of female virologist (Artie) who has to join forces with sexist mathematician (Simon) to solve a mysterious cat plague that might be more sinister than it first appears. The novel is a light-hearted thriller/whodunnit/romance/drama set firmly in the lab lit genre, jam-packed with scientists doing their science as an integral part of the plot. In fact, it’s probably the most science-y of all of my books.

My only frustration with what has otherwise been a painless process of editing and production is UK Amazon, which hasn’t responded to requests to upload the correct, current information about the book. So don’t be put off by that £18.50 price tag: the paperback price should be £9.99 (and Kindle is £3.99). The US Amazon site has the correct information.

Completely coincidentally, the publication date nicely coincides with several other geeky/sciencey/literary events I’m involved with in the coming fortnight, all of which are in London.

PubSci

On Wednesday 6th June I will be speaking at London’s PubSci – seven years after being the guest speaker at their launch event. This time I’ll be delivering a new talk I’ve just started airing: Boffins, Beards, and B-Movies: An illustrated story of science stereotypes from Socrates to Sci-fi. Packed with examples and film clips, it’s a fun exploration of the portrayal of scientists in fiction, with a more serious message about how those stereotypes can actually impair the ability of scientists to be effective messengers about all the important and crucial work that science does for humanity.

Join us upstairs at the Old King’s Head, near London Bridge station. Doors open at 6pm for a 7pm start and as usual the event is free, but there will be a whip-round to cover costs.

Fiction Lab 10th Anniversary

This month marks ten years since the launch of Fiction Lab at the Royal Institution, the world’s first monthly book group dedicated to lab lit fiction. It’s been a real pleasure presiding over this group for a decade. To celebrate, we’re throwing a special informal public event in the Ri Library on 11th June to discuss the relationship between science and literature over drinks (cash bar).

Joining me on the panel will be award-winning author Philip Ball, novelist and astrophysicist Pippa Goldschmidt and novelist and astronomer Stuart Clark, all of whom have been featured guests of honour at Fiction Lab over the years. In addition, we are pleased to welcome on the panel Stephen McGann, an actor, author and science communicator who’s currently starring as Dr Turner in the BBC hit series Call The Midwife.

Starting at 7 PM, this event is free to attend, although spaces are limited, and you can reserve your place here.

Waterstone’s Event

I’ll be one of the panellists in this 13th June event at Waterstone’s on Tottenham Court Road. From their blurb: Virtual Futures presents a panel discussion, and a series of short-story readings, on using near-future fiction to foster transformative conversations between scientists and other audiences. By imagining possible futures, near-future fiction has the capacity to seize on the science and technology currently researched in laboratory environments and take it just far enough that it can provoke audiences to think on impending potential implications for society. How can science fiction be used to create a self-reflexive capacity in scientists? How can fiction help communicate scientific research to the wider public? How can encounters between the arts, humanities, social sciences, and hard sciences and engineering be fostered?

As part of the underpinning project, three authors (not me) interacted with scientists at King’s College London and incorporated their work into short stories – a great idea.

The event starts at 6 PM for a 6.30 start – tickets can be purchased here for £6.

I’ll have books to sell and sign at all of these events, so please come along to one if you can and say hello!

——————————
More about Cat Zero

Here’s what some people have said about the book already:

Cat Zero is that rare beast, a racy novel with a sound scientific background. Postdocs will love it. Ph.D.s will gasp. And the general reader will enjoy a smart romantic thriller in which an intelligent, independent and, yes, beautiful, researcher confronts her demons while fighting to succeed in a male-dominated world. Will she find love along the way? Read it to find out—I did, and loved it!”
— Simon Mawer, author of Man Booker Prize-shortlisted The Glass Room, and Trapeze, The Fall and Mendel’s Dwarf

“Absolutely gripping. A fast-paced story that opens the lid on the secret world of the laboratory and shows us what scientists are really like—as human and fallible as the rest of us.”
— Pippa Goldschmidt, author of The Falling Sky and The Need for Better Regulation of Outer Space

“A potent mix of science, thrills and romance… Fans of Michael Crichton will love it.”
— Mark Edwards, author of number-one bestsellers The Magpies and Because She Loves Me

“Within the stylish package of a pacy thriller, Jennifer Rohn gives us a glimpse of what it’s really like to work in a scientific laboratory: the academic rivalries and jealousies, the gender politics, the frustrations of painstaking experimental work and the excitement of new ideas and breakthroughs. For once in a science-based novel, everything here is plausible – which makes it all the more alarming, and all the more compelling.”
— Philip Ball, award-winning author of Critical Mass

“A mysterious outbreak of cat plague sends an intrepid virologist on a hunt to find the source of contagion in this gripping page-turner. Nobody writes about scientists quite like Jennifer Rohn, who captures not just the technical details of research, but also the complex humanity of the endeavor.”
—Jennifer Ouellette, Cocktail Physics

“Cat Zero weaves together the complicated, sometimes archaic, social hierarchies of researchers with the thrill of a new scientific discovery. But you don’t have to know anything about science to follow along with the mysteries in this book: Why are cats falling ill in Kent? What’s going on with Artie’s strange colleagues down the hall? And will she hook up with her postdoc—or should she stay away? At the end of the book, we have some answers. But like real scientific discovery, the end is just the start of a whole new set of possibilities.”
— Eva Amsen, Easternblot.net

“This book purrs. It does that thing that cats do, playing with their toy, gently poking at it, softly lobbing it in the air, then, eventually, lunging. I’d recommend it for those who like the interplay of scientific lives, permeated with motives and mys-tery.”
— Grant Jacobs, Code For Life

“Very human scientists go about their lives and work, seamlessly blending into a fascinating tapestry as they try to solve the scientific mystery of a disease plaguing a cat population, which spills over into the human population. I loved getting to know the main character, Artie, a female scientist who deals with all of the plusses and pitfalls of being a woman, a scientist and a woman-in-science. Her personality shines through in Jennifer Rohn’s work.”
— Joanne Manaster, Read Science

“[T]he final chapters are absolute emotional roller coasters. I could not put the book down. I had to know how it ended. But I am not telling. You will have to find out for yourself. I give it five purrs and two paws up.”
— Susan Johnston, Goodreads

Here’s a spotlight on me and the novel that my lovely publishers, Bitingduck Press, sponsored in Publisher’s Weekly.

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In which a new Doctor is born

No, not that Doctor. (Besides, I’m not sure any graduate student would care to regenerate and repeat the experience for all eternity!)

My first PhD candidate, Harry Horsley, recently had his viva. Here he is, about an hour before the event:

Smiles in the face of impending Doom

The waiting was drawn out as the examiners cloistered themselves and discussed their grilling strategy. But finally Harry was called into the room, whose door clicked shut with heavy finality.

Nail-biting time

I can honestly say that I wasn’t worried for one moment that Harry wouldn’t ace it. He’s one of the most talented young scientists I’ve ever had the pleasure of working with, and of his three thesis chapters dealing with data, two are already published, and the third will be submitted in the next few weeks. But I was unaccountably nervous as the minutes ticked by: my colleagues joked that I looked paler than Harry had.

Just under two hours later, our new Doctor had emerged, victorious and with only a few battle scars, related with much laughter over champagne in the common room.

A well-deserved beverage

Yesterday, Harry gifted me with the first of what I hope will be an ever-expanding line of tomes to display with pride in the office bookshelf:

Heavy denouement

It’s been a rite of passage for me as well as Harry. My second student is finishing up his experiments this summer, while a third has just accepted an offer to join the lab (hooray!). My academic life has never been crazier: I taught my last class of the year yesterday, but now a month of full-on marking awaits. So it will be head down until June, trying to fit all of this in among my many other obligations: preparing for a clinical trial on our novel drug delivery system that the MHRA has just green-lighted in principle; working on the astonishing crop of five manuscripts that await polishing; discharging our ambitious Athena SWAN action plan; ticking off the never-ending list of small chores that accumulate like the drifts of petals and pollen swirling down and banking up on pavements all over London.

But that “school’s nearly out” feeling of my youth cannot be suppressed, evoked by the warmth of the air through an open window, the smell of freshly mown grass, the tenor of the birdsong. Some things are ending, but others are beginning.

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In which science imitates life, number 365: zones of death in public transport

I was waiting for the bus this past weekend, ridiculously early to get my son to his swimming lesson across town. Or so I thought.

We waited, and waited, and Joshua jumped up and down anxiously, looking adorable with his lobster rucksack bouncing on his back, asking over and over, “Mama, why isn’t the bus coming?”

Quite. We were rapidly reaching the point of no return, so I pulled out my phone to view the live map. There, I could see a swarm of buses studiously avoiding our position in a way that was strangely familiar:

Was it something we said?

Where had I seen that pattern before? And then I had it:

The Kirby–Bauer disk diffusion assay (via Wikipedia)

My son and I were the antibiotic, and the buses were the bacteria. And the swathe of nothingness between…was about to make us very late.

I called up an Uber – which arrived just as the bus lumbered past.

Posted in Joshua, Scientific thinking, Silliness | Comments Off on In which science imitates life, number 365: zones of death in public transport

In which age is no impediment to scientific discourse

Joshua has had quite a few vaccinations in his four-and-a-half years – the usual routine inoculations for standard childhood illnesses and a couple (chicken pox and meningitis B) that are not on the NHS menu. The last time I took him out of nursery, this time for the flu vaccine, he asked me why we were going to the doctor, and I decided to give it to him in simple terms.

With Joshua these days, you never know how much information he will end up retaining. His memory seems very fluid: he can easily forget an event that happened only moments before, but will then come out with something that he was told only once, months ago.

I wasn’t sure if he had really been paying attention, but as he was sat on my knee in the GP surgery, the kindly nurse looming over him with a syringe, he spontaneously volunteered, “I’m getting pretend germs to teach my body how to fight the REAL germs.” The nurse was visibly astounded, then regrouped and told me how happy it made her to know that someone had bothered to explain it to him.

Currently, the nursery is being decimated by chicken pox – when I picked him up today, the room was nearly deserted.

“I’m not getting the pox,” Joshua said confidently to one of his teachers. “I’ve got pretend germs. Mama, what is chicken pox?”

So I told him about viruses, and promised to show him pictures on the phone when we got home. Together, we pored over images of virions in all of their strange and beautiful glory. He liked the science fiction monstrosity of T4 phage a lot better than varicella zoster, which he proclaimed to be a “boring spiky ball”. After I tucked him up in bed, he said, sleepily, “Mama, I know I have pretend germs, but how do they REALLY fight chicken pox?” I promised I’d draw him some pictures tomorrow – antibodies, perhaps, in simple terms, and how they act.

I have tried very hard not to hold back on any scientific explanations when my son says “why”, no matter how further down the molecular or atomic rabbit hole it takes us. He seems continually up for the challenge, soaking in facts like a sponge, and enjoys the simple experiments we have done together when it turns out the answer to “why” can be demonstrated in some way. Not for the first time, it strikes me that his is precisely the age when this sort of information is best assimilated, and I always wonder if I am doing enough.

I suspect this is my cue to plug my friend Alom Shaha’s new book, Mr Shaha’s Recipes for Wonder: Adventures in Science Round the Kitchen Table. He is also giving a free talk at University College London next week called “How To be your child’s first science teacher” if you want to know more.

Posted in Domestic bliss, Joshua, Students, Teaching | Comments Off on In which age is no impediment to scientific discourse

In which I get the blues (a tale of miracle surgery)

I have a good excuse for not writing for a while: eye surgery in the new year, which made reading or writing of any kind difficult. Only now am I starting to get back to my old literary self.

I have worn glasses since about age six. My myopia had grown progressively worse over the decades until I settled at about -11 diopter with an astigmatism of about 3.5. Standard laser surgery was out of bounds, as my deeply distorted corneas didn’t have enough width to sculpt away. Soft lenses became unworkable, and then toric lenses in their turn, leaving gas-permeable hard lenses the only contact option. Finding these increasingly uncomfortable, I eventually surrendered to specs.

In my forties, I started losing my near vision too. I remember the precise moment I realized this: I was riding the New York subway, got a bit lost and realized I was physically unable to read the network map in my hand. Thus began the era of carting around three different eyeglass cases in my handbag, and shoving my glasses up onto my head to read my iPhone with one eye a few millimeters from the screen.

To make matters worse, for the past few years no optician has been able to give me a spectacles prescription that made far vision even remotely sharp. I finally went to Moorfield’s Eye Hospital to find out why.

The answer: early-onset cataracts.

I wasn’t actually unhappy to hear this. It was good to have a diagnosis at last, especially one with such a safe and reliable surgical method of treatment. Before this, I’d even been toying with the idea of treating myself to more intensive surgery. So this seemed like a good excuse to jump in feet first.

As is traditional, I underwent treatment one eye at a time. For approximately a minute, the surgeon blasted the cornea of my right eye with an impressive piece of kit known as a femtosecond laser. This was primarily to allow surgical access, but the computer had been programmed to bestow a bonus partial reduction in astigmatism. (“You’re a tough case,” the surgeon told me cheerfully. “I spent an entire evening with your scans.”)

Next, as my veins were flooded with opiates and sedation by a breezy anesthetist who looked like a rock star, and “Comfortably Numb” blasted into the theatre (I still don’t know if this was a joke), my natural lens was sonicated to bits and sucked away, and a brand-new perfectly powered artificial lens was deployed, probably as specialist as one of the eyepieces on our fancy microscopes back in the lab. It was all over in 20 minutes, efficient and painless.

The world of our senses is a neuronal construct, a fudge factor the brain cobbles together to keep us alert and safe. It’s not something most of us probably think about very often, if at all, until we encounter a drastic change. As I was wheeled into recovery, the difference was stark. I couldn’t see much out of the right eye yet, but everything was suddenly pure and silvery blue, bathed in an ethereal full-moon glow. In contrast, my knackered old left lens showed a dingy-yellow world that I didn’t much like the look of.

Which one was real? I had no idea, and I still don’t. The ageing lens does increasingly facilitate the yellow wavelength, but is the newborn lens crystal clear? Does my son see the same white-hot light that my right eye was seeing now, or is it a super-human enhancement courtesy of a lens that is clearer than any biological material could ever achieve? I can’t think of any objective way to measure this, as my experience can’t be coherently compared with anyone else’s.

But more revelations awaited. My surgery was in the evening, and it wasn’t until the next day that I properly appreciated the difference. A large number of things were newly blue, an effect that intensified when my second lens was swapped. Black looked dark navy, and some shades of blue were now full-on purple – including, it seemed, half of my wardrobe. Sunsets and sunrises featured lush, jaw-droppingly beautiful shades of violet and lavender; flames contained an iridescent core of indigo that I’d never seen before and is impossible to describe now.

Having done some reading, I now know that I’m lucky. Some color changes are more drastic, and can be quite distressing to patients (and life-changing, if their profession relies on color distinction, such as interior decorators). And while the blue shift turns out to be common, it sometimes comes at the expense of other shades, washing out greenery into a dull grey for example, and draining existence of beauty.

More than a month on, I still wander around in a daze, half befuddled and frustrated by my poor far and close vision, and half admiring the world’s transformation. My acuity improves week on week but I have a long way to go. It can take six months for the brain to adjust to the new input, and I have a hefty residual burden of astigmatism which may be correctable with more lasering, or toric lenses if not. Meanwhile, the temporary difference in acuity between my two eyes has led to a new problem: double vision in the distance, especially when I’m tired or have been using reading glasses (which are still essential for most close-up tasks beyond reading). I now have a grand total of four eyeglass cases in my bag – two different powers of readers for very close work and screens, unpowered lenses with a rather obtrusive prism in one eye to correct the double vision when I can’t bear it any more, and sunglasses for those rare bright days when the white light becomes overwhelming.

Yes, I’m partially disabled now, worse than before for a few months: things like working from a cookbook or assembling something from instructions have become so troublesome that my brain keeps urging me to avoid them. But equally, I feel I’ve been blessed with an astonishing miracle. I can see, without glasses, for the first time in my conscious life.

A world without glasses – I never thought I’d see the day.

Posted in The ageing process | Comments Off on In which I get the blues (a tale of miracle surgery)

In which we look back at top 2017(ish) lab lit fiction

As the old year dribbles to a close under heavy grey skies and relentless rain here in southeast England, just a quick note to point you towards a recent interview of me on US National Public Radio, chatting to host Heather Goldstone about a few science-in-fiction novels that kept me busy over the past year. They’re all either out in 2017, or the paperback versions were.

Listen here!

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In which we wind down

I’ve been off work for a few days, but the incompatible clash of exhaustion and adrenalin which characterizes my life in academia has yet to ebb. These days it takes a full week to come down from the jaw-clenched crush of forward propulsion that sees me through a busy term.

It doesn’t help that a few outstanding work tasks smuggled themselves home with me: a paper revision; signing off some data on the industrial project; fielding a pursuing wave of emails that only today is starting to taper off.

Here at home, we are ready for Christmas. The final packages have been delivered, the larder is stocked, the tree and decorations are all up. The pipeline of paperwhite narcissus I’ve been forcing in the garage for the past few months are obediently flowering in sequence in the warmth of our living room. We’ve made a gingerbread house, have all the ingredients for the annual batch of Julpepparkakor, and have remembered to load up the next morning’s drawer of Joshua’s advent calendar house in advance, every single night. Richard has made his incredible sausage rolls, and is about to turn his hand to home-made mince pies.

I miss my Mom the most this time of year. It was she who taught me how to make the pepparkakor, and who always had bulbs flowering on time. I miss the proper Ohio winters, burrowing through several feet of snow, going numb on the sledding hill, ice-skating on lakes in the woods, the swirling filigree of jack frost on all of the window panes. Here in southeast England, after a few weeks of zero temps, we’ve reverted to the usual Christmas norm: moist and mild, the intense green of holly and ivy, muddy grass, fallow fields under weak sun.

Meanwhile, the precious time off is melting away far too quickly. Any day now, I hope to shake the residual end-of-year blues and inhabit the joys of Christmas in full.

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In which we’re in business: Cat Zero officially for sale!

Just a quick note to say that my upcoming third lab lit novel, Cat Zero, is now available for pre-order on Amazons near and far (UK and USA)!


Still with placeholder cover featuring the neighbour’s cat Sergei!

There should be a Kindle edition too.

Happy days!

PS. If you’re a blogger or journalist and want an advanced review copy, please drop me a line.

Note added 1 December 2017: The high UK Amazon paperback price appears to be a glitch. We expect to sort this out, and pre-orders will only be charged at the right eventual price. There will be a reasonably-priced Kindle option too in due course.

Posted in LabLit, Writing | 1 Comment

In which life slips past

Time is passing.

My baby son has somehow turned four years old, and a very significant birthday approaches in a month’s time for me as well.

Birthday Boy

The seasons are changing. We’ve stopped watering the withered tomato vines, seen the last of our courgettes swell, dug up the final potatoes, cut down the tall sunflower canes. We collect hops for beer, windfall apples to make cider. Filling up the house with enticing aromas, we prepare chutneys and jams from last year’s harvest to make room in the chest freezer for this year’s overspill.

Hops

In various beds, the carrots, chard, celery, beets, red cabbage and peppers still yield, and there’s always a fresh bouquet on the table: roses, dahlias, passion flower. Our Florence fennels never swelled, but waiting in the wings are parsnips, sweet potato and a promising crop of quince.

Dahlia

Harvest

I retreat to my garden increasingly as academic stress builds, even as the daylight hours shrink. I have always loved this time of year – though I never truly remember how much until it’s happened. I’ve started wearing a coat and scarf against the chill as I scuffle home through fallen leaves on the way from the station. The central heating is finally in use, and we light candles to ward off the rainy darkness.

I’m secretly horrified by the horse-chestnut blight that looks set to erase conkers from the cultural landscape of England, and am saddened that my son might not remember the last time he held a burnished, healthy specimen in his chubby palm.

Blight

My newly enlarged lab is settling in, and I am enjoying the bemused feeling of activity happening when I’m not looking, initiative being taken, self-organization processes clicking into place. I get copied into emails requesting strains and reagents from far-flung labs; the ordering spreadsheet gets populated with interesting-looking reagents when I’m looking the other way; pub sessions occur.

Tequila shots may even have been downed after our lab brainstorm session.

A new crop of students has arrived, boisterous, alive, full of potential. The course has grown from a little more than thirty students in 2014 to nearly 90 this year, and it feels good to have been in on the process from the beginning, to have helped create something new and different from nothing. Every time an entire room full of young people laughs at one of my jokes, or treats me to a round of applause after my world-famous “Reconstruction of G-Protein-Coupled Receptor Signalling Using Chairs and a Handbag” routine, I feel like a million bucks.

Grant applications go out, manuscript decisions come in. Somehow, I hold it all together.

At the moment, I’m confident, happy and riding high, yet aware of the undercurrent of wistfulness that autumn always brings.

Time is passing.

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