On Biological Modelling

Oily Spaghetti Model
#4 Nuclear Pore (internal) (oily spaghetti model)

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On biological modelling

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Lipid raft
#3 Lipid raft

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Standard Model

As Tyrant for Life one of my (self-appointed, obviously) responsibilities is to keep an eye on the goings-on over at our outpost in the Gamma Quadrant. So it was that on Thursday lunchtime that I was catching up on the comment thread of Stephen’s latest post. Something there caught my eye, and in five or ten minutes I’d used that inspiration to scribble the following poem. Enjoy!

Standard Model

When a proton
   In desperation
First grabbed an electron
   And gave unwittingly
To an undiscovered country
   Stars and water and airships
Did it feel
   In some quark-like fashion
The same primal urge
   That keeps my heart
In orbit
   Around the sun of you?

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On biological modelling

Nuclear Pore
#2 The Nuclear Pore

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On biological modelling

Ribosome

#1 The Ribosome

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(Talkin’ ’bout) my generation

Someone, somewhere, has been viewing my LinkedIn profile.

I know this, see, because I’ve had a couple of calls and emails from various recruitment agencies, and I’ve seen that recruitment ‘specialists’ have left their footprints all over LinkedIn. One of them called me out of the blue at work. When it became clear that I’m not looking to leave my current job at the moment he asked if I knew anyone else who might be appropriate. He subsequently sent me another couple of openings.

The thing is, of course I’ll help my friends find jobs, and if we have an opening I’ll think about who may be looking and be suitable. But I’m not about to become a freelance, unpaid recruitment service.

None of this is new (unless you’ve never worked outside academia, perhaps). The IT field in particular seems to specialize in boneheaded recruitment tales—or maybe sysadmins and programmers and the like just complain about it more. There’s probably a TV series in there, if it hasn’t been done already.

Anyway, this recruiter was pretty good, on the whole. We had a chat about where are nice places to work and live, and the kind of salaries one might expect in this business, and he hasn’t hassled me about sending him business. So, I like that.

However, I received an email from another recruitment agency that, frankly, makes me want to run a mile. The agency appears to be London-based (at least, that’s what I’m getting from a whois on the domain name. They don’t appear to have a website), and they certainly seem to want to appear knowledgeable about my field, but the English doesn’t exactly inspire confidence:

“Account manager with a well know agency based in London.”

“Programme Director directing the role out and development of a medical education program across Europe […] delivering events throughout Europe to support the campaigns roll out.”

“Client Services Director for a well know medical education agency”

“have a chat about you options going forward”

Ouch, ouch, ouch.

Yes, I know that this cove is a recruiter and neither a writer nor an editor. But he’s trying to attract writers and editors, and if there’s one thing likely to make writers and editors reach for the valium (or a rifle, whichever’s closest) it’s stupid mistakes in any written material that leaves the building. So if you really do know your field, and you want to get the person to fulfill your client’s vacancies, you’d better make sure everything is spelled correctly (and that you know the difference between ‘role’ and roll’, for example).

(Admittedly the job titles in this particular email tended to be account- and project manglement-related; but those positions are frequently filled by wordsmiths in this business. And if they’re not, the manglers in question will have had their ears sufficiently burned by wordsmiths that they know how important all this malarkey is. One of my very young account manglers is in fact so well trained that she’ll run all her client contact reports by me before sending them off.

Seal of approval
)

So, Mr Recruiter, no I will not be discussing potential rolls in any of your well know agencies, at Program nor Programme director level—at least not with with your.

And please, please please please, understand that “Salary – highly competitive salary and package” is as meaningless as the phrase “trustworthy politician”. Nobody’s going to tell you they pay fucking peanuts, are they?

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A Christmas Fantasy

You know that thing you do where you read something, and completely misread a single word, and then go back and it’s normal and how it was meant to be?

That happened to me a couple of days ago. I misread a single word on a postcard from a certain shop, and at the speed of thought an entire world of possibilities opened up to me, based on that misreading. But in the space of a heartbeat I saw what was really written, which wasn’t nearly so interesting.

That didn’t stop me writing a poem about it though. Enjoy!


A Christmas Fantasy

In the post-Christmas languor
    Approaching the New Year—
Heart and belly sated
    Full with seasonal cheer—
While bagging up the gift-wrap,
    Under a pile of mail
I glimpsed a red-trimmed postcard:
    Orvis having a sale.

Under the pizza leaflets,
    Envelopes for the poor,
Local IT repair firms—
    All offered through my door;
Proclaimed the Orvis postcard
    (I’m sure it said, I swore!),
For sale: hundreds of poems,
    All “at half-price or more.”

“What are these wondrous tidings?”
    I said, and in my haste,
Pulled on my boots and raincoat,
    “There is no time to waste!
I’ll go straight to Dover Street
    To find this sacred store,
There to buy us some poems
    All for half-price or more.”

In my granddad’s day, he got
    A sonnet for his daughter.
Even then they were not cheap—
    Sixpence for a quarter.
But he would be shocked to see
    At the Orvis store,
Poems of all size and shapes
    For sale; half-price or more.

In my mind I saw it clear:
    New poems by the pound!
Finely graded, freshly picked,
    In spoonfuls heaped and round.
Or, perhaps, they’d sell by length,
    Laid out across the floor:
I’d get three yards of sonnet
    And pay half-price or more.

I’d try all their limericks
    And even haikus too—
And to the fair assistant,
    I’d say, “And one for you?”
I’d hurry then, and take the card
    (‘Cause it would be a mess
If what they really meant to say
    Wasn’t “half-price or less”).

As I reached to take the card,
    My hand upon the door,
A pizza leaflet shifted;
    I saw the line once more:
An ‘i’ and ‘t’ were covered—
    Not ‘poems’ at the store—
It read “Hundreds of items
    All at half-price or more.”

Dashed was my Christmas vision—
    There was no sacred store
With yards and heaps of sonnets
    And verses on the floor.
Curse your eight-pointed snowflakes!
    (Your grammar’s also poor.)
Yet still I’ll dream of poems
    Hundreds: half-price, or more.

    

Bah humbug.

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More to a sinner

When people ask who were my influences, I find it difficult to give a straight answer. I cannot name a childhood hero in whose footsteps I wanted to follow, neither was there someone whose guidance or mentoring I’d particularly like to single out. I do have a number of scientific heroes now, people of whom I became aware as I learned more about the world, but they were mostly post-hoc, as it were.

We could however point to my English teacher when I was barely 12, who told my parents I should go to Oxford. We might mention Sir Fred Hoyle, who collaborated with Chandra Wickramasinghe on the concept of panspermia. I remember avidly reading a present from my parents, Diseases from Space, which more than anything else I can think of inspired my interest in science. I had the honour of working with Wickramasinghe on a special edition of The Biochemist magazine; unfortunately, although he wrote for us, I never got to meet Hoyle himself.

Someone else who left a huge impression on me was Lady Margaret Florey, who I met just the once, but whose reputation and life were very much an inspiration. Margaret Jennings, as she was then, conducted the animal tests of penicillin at the Sir William Dunn School of Pathology in Oxford in the early 1940s. Other influences would have to include Sir Cumference, aka Neddy Seagoon, aka Sir Harry Secombe, who died just a few months before Hoyle. I was very fortunate to see him in ‘Pickwick’ at the New Theatre in Oxford, where he cracked up the cast and made me cry with laughter.

And I should also mention Sir Patrick Moore, who died at the weekend. Somewhere I still have at least one of his astronomy books for children, to go with my memories of Sky at Night. I was over the moon (to coin a phrase…) that he lent his support to our original Science is Vital campaign.

What do these people have in common?

On Sunday, an hour or two after I learned of Sir Patrick’s death, I poked around on Twitter for a little bit. It wasn’t long before, in between the tributes and expressions of sadness, that I found the tweet I’d been dreading. You know, the one along the lines of “That right-wing bigot?”. As if we didn’t know his views. As if they lessened his brilliance. As if that somehow negated the positive influence and inspiration he had been.

As if it mattered.

The thing is, we all have something wrong with us. There is, in each and every one of us, something that other people will find distasteful, perhaps even obscene. We all have faults; none of us is perfect in every way. “We all,” as Isaiah writes, “like sheep, have gone astray”.

But should that detract from the good and the beautiful things we human beings can do? Does it not rather make the good even more marvellous? That in our fallen and broken humanity we can create great works of art, make heartbreakingly beautiful music, put people on the moon and probe the secrets of life and the fabric of the universe (and, sometimes, even explain what we’re doing) makes those achievements more than wonderful. What’s more, it means nobody is excluded from brilliance, from aspiration, just because they can be a bit of a prick sometimes.

We are in a strange position, we humans. We have this amazing brain, and abstract concepts such as love, justice, selflessness, mercy and compassion; we have dreams and fears and hopes and hates—yet we are fundamentally broken. Terry Pratchett has it nailed when he talks about the “place where the falling angel meets the rising ape”.

So as one ape to another: thank you for everything, Sir Patrick; and everyone else, too.

Posted in Ill-considered rants, People, Personal | Tagged , , , , , , | 5 Comments

On being the blogfather

More than a little while ago I used to write a not unsuccessful weblog. This was all very nice and froody and I had quite the following. Then something happened.

What happened, and I’m still not really sure how or why it happened, is that I became famous—or at least, small values of famous. And that changed things a bit. I was no longer able to write sarcastic, somewhat bitter posts about random happenings in the lab, because people knew who I was.

This was brought home to me very clearly once upon a time. I bitched about a perceived injustice. I felt that a reasonably senior person was unreasonably muscling in on a manuscript I’d written. So, naturally, I wrote, somewhat inadvisedly perhaps, about it on my blog at at time.

Ouch

The reasonably senior person recognized the situation, recognized himself maybe, and I got called in for a well-deserved ear-bashing—after my immediate boss had his own ears bashed.

Double ouch

As it turns out, this perceived injustice was just that—perceived—and we had a chat and a cup of cocoa and sorted it all out. Reasonably senior person was, in fact, a fan of my blog, which made things worse. At least, it made me think twice about what I could write.

Since then, as I say, I became small-values-of-famous, left the lab a little while after that, and started working in a real job. Those things are not necessarily related, although from certain angles they might be. Either way, this combination of events not only restricted my blogging material, but also restricted my freedom in what I could write about—not simply because I was afraid of getting the sack, but because the interesting things that happen in the lab simply don’t happen in industry. Or if they do, the protagonists are more readily identifiable.

Rock, hard place, me.

Also, I’m feeling guilty that I haven’t written a blog post since September. How the frig did that happen?

Now, however, having spent the evening waiting for Jenny to find her way home from Doncaster of all places, it strikes me that perhaps the time is right to (let’s not beat around the bush) recycle some old material. For, although small-values-of-famous as I might be, not all my war stories and anecdotes have been shared with all my different audiences. Ha ha, yes, I’ve been holding out on you. So, my stated intention is to go through my archives, dulled as they are by the fog of time, and bring them right up to date and make them shockingly relevant.

After all, although science and art may change with time, human nature (pace Heraclitus) is constant.

Dun dun DUNNNNN.

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